A New EQA Scheme for Immunosuppressants: Applicability for Mass Spectrometry and Other Analytical methods

Immunosuppressant drugs such as tacrolimus, cyclosporine, sirolimus and everolimus require accurate and reliable therapeutic drug monitoring due to their narrow therapeutic range and clinical importance. Analytical methods used for these measurements vary between laboratories, including liquid chromatography-mass spectrometry (LC-MS/MS) and immunoassay-based techniques. External quality assessment (EQA) is essential to ensure reliability of results across different methods. This study presents Labqualityʼs pilot study results of a new EQA scheme for immunosuppressant measurements.